Reactivity of N-Benzyl-3-nitrophthalimide: A facile access to isoindolo[1,2-d][3,5]benzothiazocine derivatives

Article abstract of DOI:10.1002/jhet.5570370622

A functionalized isoindolo[1,2-d][3,5]benzothiazocine 2B has been synthesized in three steps from the nitro-imide derivative 5. The key step of this sequence was the cyclization of the thioglycolic acid derivative 9 under acidic conditions. An evaluation