CHLORURE D'ALUMINIUM, CATALYSEUR D'ACETONISATION DANS LA SYNTHESE DU 4-DESOXY-1,2-O-ISOPROPYLIDENE-β-DL-threo-PENTOPYRANOSE ET DE SES DERIVES

Article abstract of DOI:10.1016/S0008-6215(00)85430-0

4-Deoxy-1,2-O-isopropylidene-β-DL-threo-pentopyranose (6) has been synthesized according to a new method of acetal formation with acetone that employs aluminium chloride as the catalyst.The best yield was obtained when the acetonation was conducted on a column of silica gel as a heterogeneous phase.The 3-azido and 3-oximino derivatives of 6 were prepared as potential synthetic intermediates for the preparation of amino sugar nucleosides.