Dithio and thiono esters, LVII: Synthesis of dithio and thiono esters of N-protected β- and γ-amino acids

Article abstract of DOI:10.1002/ardp.19933260505

The N-protected β-aminonitriles 1 were transformed into the imidoester or thiolimidoester hydrochlorides 2 or 3 according to Pinner and sulfhydrolyzed with H₂S to give the N-protected β-amino thiono esters 4 or dithio esters 5. Alkylation of th