Journal of Medicinal Chemistry p. 1144 - 1149 (1983)
Update date:2022-08-04
Topics:
Yamada, Toshihiro
Shimamura, Hiroshi
Tsukamoto, Yoshitsugu
Yamaguchi, Azuma
Ohki, Masahiko
3(2H)-Pyridazinone derivatives having a 2-cyanoguanidine moiety, as well as a sulfur or an oxygen atom in the alkylene side chain, were synthesized and evaluated for gastric antisecretory and antiulcer activities.The key intermediates, free amines having
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