Pyridazinones. 3. Synthesis, Antisecretory, and Antiulcer Activities of 2-Cyanoguanidine Derivatives

DOI: 10.1021/jm00362a011

Source and publish data:

Journal of Medicinal Chemistry p. 1144 - 1149 (1983)

Update date:2022-08-04

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Authors:

Yamada, Toshihiro

Shimamura, Hiroshi

Tsukamoto, Yoshitsugu

Yamaguchi, Azuma

Ohki, Masahiko

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Article abstract of DOI:10.1021/jm00362a011

3(2H)-Pyridazinone derivatives having a 2-cyanoguanidine moiety, as well as a sulfur or an oxygen atom in the alkylene side chain, were synthesized and evaluated for gastric antisecretory and antiulcer activities.The key intermediates, free amines having

Full text of DOI:10.1021/jm00362a011

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