Synthesis of Functionalized Quinoline Derivatives by Annulation of Pyridines

Article abstract of DOI:10.1021/jo00323a016

Thiophenyl and sulfonylphenyl groups were introduced on each methyl group of 2,3-lutidine (1), and the reactivity of the adjacent carbanions has been examined.When both methyl groups of 1 were substituted with sulfur groups, regioselective alkylation of t