Tetrahedron Letters p. 1957 - 1960 (1981)
Update date:2022-08-03
Topics:
Artaud, I.
Viout, P.
In the presence of MOH (M=Li, Na, or K), Ph-CHCl-CO2i.Pr (1) and CH2=CHCO2t.Bu in dioxane lead to the expected formation of cyclopropyl esters and to the concurrent saponification of 1 to Ph-CHCl-COO(1-)*M(1+).The very important influence of the cation size and the smaller one of the water on the competition between the two reactions due to the basic or the nucleophilic attack of 1 by MOH is evidenced.The process can be orientated to the cyclopropanic esters formation by using dehydrated KOH.
View MoreContact:0086 371 65711996
Address:Jalan 4/3, Kawasan Perindustrian Serendah, 48000 Rawang,
NINGBO PANGS CHEM INT’L CO.,LTD.
Contact:+86-574-27666845
Address:FLOOR 21,BUILDING NO.11,XIN TIAN DI,NO.689 SHI JI ROAD,NINGBO CHINA
website:http://www.shengmaochem.com
Contact:86-27-82853423, 82819281
Address:Rm 202, A Unit Huaqiao Building No. 2, Lihuangpi Road, Wuhan, China
LIAOYANG TENGYUAN FOOD ADDITIVE FACTORY
Contact:+86-419-5807666
Address:Haodianzi village,Hanling Town,Liaoyang county
Tianjin Jingye Fine Chemicals Co., Ltd.
Contact:+86-15722078107; +86-22-26911407
Address:Bohua Fine Chemicals Base of Petrochemical Industry Park, Nanhuan Road, Dagang District, Tianjin, 300271, P. R. China
Doi:10.1021/acs.joc.6b00848
(2016)Doi:10.1021/ol203232m
(2012)Doi:10.1002/anie.201307846
(2014)Doi:10.1016/j.saa.2012.10.043
(2013)Doi:10.1080/07328303.2011.610544
(2011)Doi:10.1021/om2009793
(2012)
