A radical-organometallic glycine synthon. Preparation of homochiral heterocyclic α-amino acids

Article abstract of DOI:10.1016/S0040-4039(00)61614-3

Co(Acac)₂ reacts with (1) and (d)-menthyl N-BOC-2-bromoglycinates to give (1)- and (d)-menthyl N-BOC-3-acetylnorvalinates, which are converted into homochiral 2-(3,5-dimethyl-4-pyrazolyl)glycine and 2-(3,5-dimethyl)-4-isoxazolylglycine.