Synthesis, antioxidant properties and radioprotective effects of new benzothiazoles and thiadiazoles

Article abstract of DOI:10.1016/j.bmc.2009.05.039

In this work, we report the synthesis and characterization of new compounds derived from benzothiazoles and thiadiazoles. We observed that structural modifications on these skeletons affected the antioxidant activity. Thiol and aminothiol compounds derived from thiadiazoles and benzothiazoles showed an interesting antioxidant property. The radioprotective activity has also been evaluated in mice. Some of these compounds could be good radioprotectors.