European Journal of Organic Chemistry p. 5276 - 5281 (2013)
Update date:2022-08-04
Topics:
Yang, Yiwen
Gong, Hao
Kuang, Chunxiang
A mild and efficient method for the direct alkenylation of 5-pyrazoles by Pd-catalyzed C-H bond activation is described. The reaction smoothly proceeds at room temperature to provide products in up to 92 % yield. Heterocycles containing the 5-pyrazolone moiety are synthesized by an oxidative Heck-type reaction. The direct alkenylation of 5-pyrazolones at room temperature through Pd-catalyzed C-H bond activation is described. Copyright
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