Journal of Medicinal Chemistry p. 4990 - 5000 (2005)
Update date:2022-07-29
Topics:
De Tullio, Pascal
Boverie, Stéphane
Becker, Bénédicte
Antoine, Marie-Hélène
Nguyen, Quynh-Anh
Francotte, Pierre
Counerotte, Stéphane
Sebille, Sophie
Pirotte, Bernard
Lebrun, Philippe
A series of 6,7-disubstituted 4H-1,2,4-benzothiadiazine 1,1-dioxides bearing a short alkylamino side chain in the 3-position were synthesized. These compounds were tested on rat pancreatic islets and on rat aorta rings. In vitro data indicated that in mos
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