HIGHLY EFFICIENT LIPASE-CATALYZED ASYMMETRIC SYNTHESIS OF CHIRAL GLYCEROL DERIVATIVES LEADING TO PRACTICAL SYNTHESIS OF (S)-PROPRANOLOL

DOI: 10.1016/S0040-4039(00)80711-X

Source and publish data:

Tetrahedron Letters p. 5173 - 5176 (1988)

Update date:2022-08-03

Topics:

Authors:

Terao, Yoshiyasu

Murata, Masakazu

Achiwa, Kazuo

Nishio, Toshiyuki

Akamtsu, Minoru

Kamimura, Minoru

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Article abstract of DOI:10.1016/S0040-4039(00)80711-X

Efficient asymmetric synthesis of chiral glycerol derivatives was realized by lipase-catalyzed reaction in organic medium and its application for synthesis of (S)-propranolol was demostrated.

Full text of DOI:10.1016/S0040-4039(00)80711-X

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