Bioorganic and Medicinal Chemistry Letters p. 849 - 852 (1996)
Update date:2022-08-03
Topics:
Jew, Sang-Sup
Kim, Myoung Goo
Kim, Hee-Jin
Roh, Eun-Young
Cho, Youn-Sang
Kim, Joon-Kyum
Cha, Kyung-Hoe
Lee, Kang-Keun
Han, Hyun-Jung
Lee, Heesoon
Sixteen (RS)-20-desethyl-20-substituted camptothecin analogues were designed and prepared by total synthesis. These analogues were evaluated for cytotoxic activity against five tumor cell lines. The cytotoxic activity of compound 14f was shown to be comparable to that of camptothecin.
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Doi:10.1271/bbb.60.862
(1996)Doi:10.1016/0040-4039(96)00612-0
(1996)Doi:10.1021/jo00052a060
(1992)Doi:10.1016/S0960-894X(98)00352-7
(1998)Doi:10.1002/adsc.200700084
(2007)Doi:10.1246/bcsj.53.1065
(1980)
