Radical-mediated synthesis of bridgehead-substituted bicycloalkanes. A convenient route to the bicyclo[3.2.1]octyl system

Article abstract of DOI:10.1021/jo00116a044

Cyclization of the (3-methylenecyclohexyl)ethyl radical (9) to the isomeric 1-bicyclo[3.2.1]octylmethyl radical (10) occurs with an activation energy of 11.6 kcal mol^-1, a barrier which compares favorably with the calculated value of 12.6 kcal