Nucleophilic displacement of the chelating bis(sulfoxide) from cis-[meso-1,2-bis(phenylsulfinyl)ethane]dichloroplatinum(II) and cis-[rac-1,2-bis(phenylsulfinyl)ethane]dichloroplatinum(II)

Article abstract of DOI:10.1021/ic50215a017

The kinetics of ring opening, by amines in 1,2-dimethoxyethane, have been measured for two bis(sulfoxide)-platinum(II) isomers. The results make possible a discussion of the differences between the two isomers, in comparison with other platinum(II) complexes, in terms of absolute reactivity, nucleophilic discrimination, and steric retardation effects.