Diversity-oriented synthesis for novel, selective and drug-like inhibitors for a phosphatase from Mycobacterium tuberculosis

DOI: 10.1039/c4md00099d

Source and publish data:

MedChemComm p. 1496 - 1499 (2014)

Update date:2022-07-29

Topics:

Authors:

He, Rongjun

Bai, Yunpeng

Yu, Zhi-Hong

Wu, Li Wu, Li

Gunawan, Andrea Michelle

Zhang, Zhong-Yin

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c4md00099d

Mycobacterium protein tyrosine phosphatase B (mPTPB) is a potential drug target of tuberculosis (TB). Using small molecule inhibitors of mPTPB could be a treatment to overcome emerging TB drug resistance. Using a Diversity-Oriented Synthesis (DOS) strateg

Full text of DOI:10.1039/c4md00099d

Products guided by the article

Product name:5-acetylamino-2-methoxycarbonyl-1-acetoxybenzene

Cas No:38059-73-3

R&D Labs maybe for 38059-73-3

Hangzhou Maytime Bio-Tech Co.,Ltd.

website:http://www.maytime.com.cn

Contact:+86-571-88925295 88920965

Address:NO.2-1701 Ganghui Central Ningwei Street, Xiaoshan Hangzhou Zhejiang China
Xiamen Goodhealth Pharmchem Co., Ltd.

Contact:0086-592-2097683

Address:404R No.2 54# Minzu Rd., Xiamen, China
Wuhan HengHeDa Pharm Co., Ltd

Contact:86-27-84888681

Address:Wuhan economic & technology development zone
shanghai Tauto Biotech Co., Ltd

website:http://www.tautobiotech.com/en/index.htm

Contact:+86-21-51320588 ext. 8025

Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA
RongCheng K&S Chemical Co.,Ltd

Contact:0631-7336369

Address:rongcheng ,shandong province china

Relevant to this article

Doi:10.1002/hlca.19540370122
(1954)
AAA in KAT/DYKAT processes: First- and second-generation asymmetric syntheses of (+)- and (-)-cyclophellitol

Doi:10.1002/1521-3765(20010903)7:17<3768::AID-CHEM3768>3.0.CO;2-C
(2001)
Doi:10.1021/ja01192a027
(1948)
5-(Tryptophyl)amino-1,3-dioxoperhydropyrido[1,2-c]pyrimidine-based potent and selective CCK₁ receptor antagonists: Structure-activity relationship studies on the central 1,3-dioxoperhydropyrido[1,2-c]pyrimidine scaffold

Doi:10.1021/jm010898i
(2001)
Iron-Catalysed Remote C(sp³)?H Azidation of O-Acyl Oximes and N-Acyloxy Imidates Enabled by 1,5-Hydrogen Atom Transfer of Iminyl and Imidate Radicals: Synthesis of γ-Azido Ketones and β-Azido Alcohols

Doi:10.1002/chem.201901079
(2019)
A phenol-imidazole pro-ligand that can exist as a phenoxyl radical, alone and when complexed to copper(II) and zinc(II)

Doi:10.1039/b212209j
(2003)

Article Doi