8-Chloro-1-methyl-6-phenyl-4H-s-triazolobenzodiazepines with Substituents at C-4

DOI: 10.1021/jm00180a012

Source and publish data:

Journal of Medicinal Chemistry p. 643 - 647 (1980)

Update date:2022-08-04

Topics:

Authors:

Hester, Jackson B.

Rudzik, Allan D.

Voigtlander, Philip F. Von

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Article abstract of DOI:10.1021/jm00180a012

A series of 8-chloro-1-methyl-6-phenyl-4H-s-triazolo<4,3-a><1,4>benzodiazepines with substituents at C-4 was prepared and evaluated for antianxiety potential.It was found that substitution at this position generally decreased the activity in this series.

Full text of DOI:10.1021/jm00180a012

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