Phospho sulfonic acid: An efficient and recyclable solid acid catalyst for the solvent-free synthesis of α-hydroxyphosphonates and their anticancer properties

Article abstract of DOI:10.1039/c5nj00312a

As a means of developing biologically active compounds, a series of α-hydroxyphosphonates, ArC(OH)PO(OR)₂ (Ar = 5-G-2-OHPh; R = Me, Et, iPr, Bu; G = H, Br, Cl, NO₂), have been synthesized by reacting diversely substituted salicylalde