Tetrahedron Letters p. 3255 - 3258 (1996)
Update date:2022-08-03
Topics:
Burgess, Laurence E.
Gross, Elizabeth K. M.
Jurka, Joe
Epoxides generated from cyclic ene carbamates are effective N-acyl iminium ion precursors and allow for the preparation of β-hydroxy, α-substituted piperidines and pyrrolidines. The total synthesis of racemic Febrifugine is also described.
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Doi:10.1021/acs.orglett.0c01690
(2020)Doi:10.1016/j.ejmech.2021.113516
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