An efficient route for synthesis of 5,6-diphenylimidazo-[2, 1-b]thiazoles as antibacterial agents

Article abstract of DOI:10.1002/jhet.5570370443

The reaction of 4,5-diphenylimidazol-2-thione (1) with aromatic ketones 2a-i using the acidified acetic acid method afforded the 4,5-diphenyl(2-imidazolylthio)acetophenones 3a-h in good yields. While, the cyclized product 4i was obtained directly upon rea