Syntheses and absolute stereochemistries of UPA0043 and UPA0044, cytotoxic antibiotics having a p-quinone-methide structure

DOI: 10.1021/ol016960n

Source and publish data:

Organic Letters p. 4291 - 4294 (2001)

Update date:2022-08-04

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Authors:

Takao, Ken-Ichi

Sasaki, Tomoko

Kozaki, Tomohito

Yanagisawa, Yumiko

Tadano, Kin-Ichi

Kawashima, Akira

Shinonaga, Hideki

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Article abstract of DOI:10.1021/ol016960n

(Formula Presented) The first syntheses of new antibiotics UPA0043 and UPA0044 were accomplished starting from commercially available 18β-glycyrrhetinic acid and vanillin. The present syntheses involve the coupling of a sesquiterpenoid aldehyde and an ary

Full text of DOI:10.1021/ol016960n

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