
Synthesis p. 990 - 992 (1987)
Update date:2022-08-05
Topics: -Synthesis
Sharma, S. D.
Mehra, Usha
Khurana, J. P. S.
Pandhi, S. B.
Cycloaddition of dithiocarbonimidate 1 to the ketene generated in situ from phenoxyacetylchloride in the presence of triethylamine affords the 4-dithioalkyl-2-azetidinones 2 in good yields.Facile conversion of 2 to the 4-unsubstituted β-lactams 3 can be accomplished by desulfurization with Raney-Nickel.Formation of several interesting products during attempts to bring a carbonyl function at C-4 in 2 has also been described.
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