
Journal of the Chemical Society. Perkin transactions I p. 1941 - 1944 (1996)
Update date:2022-08-05
Topics:
Chambers, Richard D.
Sandford, Graham
Sparrowhawk, Matthew E.
Atherton, Malcolm J.
1,3-Dithiolanes, prepared from diaryl ketones, react with elemental fluorine-iodine mixtures to give the corresponding difluoromethylene derivatives. Under the same conditions, thioglycosides give glycosyl fluorides in good yields. Reaction of 1,3-dithiolanes with fluorine in aqueous acetonitrile provides a remarkably mild method for efficient deprotection to the parent ketone.
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