Organic Letters p. 2831 - 2835 (2021)
Update date:2022-08-05
Topics:
Yamane, Daichi
Tanaka, Haruna
Hirata, Akihiro
Tamura, Yumiko
Takahashi, Daichi
Takahashi, Yusuke
Nagamitsu, Tohru
Ohtawa, Masaki
A one-pot γ-lactonization of homopropargyl alcohols via an alkyne deprotonation/boronation/oxidation sequence has been developed. Oxidation of the generated alkynyl boronate affords the corresponding ketene intermediate, which is trapped by the adjacent hydroxy group to furnish the γ-lactone. We have optimized the conditions as well as examined the substrate scope and synthetic applications of this efficient one-pot lactonization.
View MoreContact:13357117572
Address:No.149 Shiji dadao Road.
SEA BRGIHT INDUSTRY CO.,LIMITED
Contact:0086 755 8622 3990
Address:Rm 17B3,GuangCaiXinTianDi Bldg,GuiMiao Rd,NanShan District,Shenzhen,China
TIANJIN DONGRUXIANG MINERALS MARKETING CO.,LTD(expird)
Contact:22-58516360
Address:tianjin
Nanjing Chemical Material Corp.(NCMC)
website:http://www.njchemm.com
Contact:0086-25-83172879
Address:B12 Technology and Innovation Building, Nanjing Tech University, No.5 New Model Road
Qingdao S. H. Huanyu Imp. & Exp. Co., Ltd.
Contact:86-532-88250866
Address:Room 615, World Trade Centre Building B, Hongkong Middle Roda 6#, Qingdao, Shandong, China
Doi:10.1039/b106479g
(2002)Doi:10.1016/j.tetlet.2009.02.060
(2009)Doi:10.1021/ja00972a067
(1966)Doi:10.1021/jo00915a004
(1974)Doi:10.1016/0040-4020(73)80047-X
(1973)Doi:10.1016/j.tetlet.2010.03.029
(2010)
