Aminothiazines et aminothiazoles analogues ouverts du levamisole: synthese et approche du mode d'action nematicide

Article abstract of DOI:10.1016/0223-5234(89)90011-1

New compounds with thiazoline or dihydrothiazine rings substituted by alkylamino or arylamino groups were synthesized and screened in vitro against three Nematodes.Inhibition of fumarate-reductase activity was also evaluated.For all in vitro anti-parasitic tests, dihydrothiazines were more potent than corresponding thiazolines derivatives, however, thiazolines showed a greater inhibition of fumarate-reductase.