Tetrahedron Letters p. 857 - 860 (2002)
Update date:2022-08-03
Topics: Synthesis Proposed structure
Okue, Masayuki
Kobayashi, Hiroyuki
Shin-ya, Kazuo
Furihata, Kazuo
Hayakawa, Yoichi
Seto, Haruo
Watanabe, Hidenori
Kitahara, Takeshi
A stereoselective total synthesis of the proposed structure of kaitocephalin (1) was accomplished starting from L-proline and D- and L-serines. However, its 1H NMR spectral data and retention time on HPLC were not identical with those of authentic natural kaitocephalin. The revised stereochemistry of natural kaitocephalin, (2R)-isomer (16), was inferred from further experiments employing diastereomers and model compounds.
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Doi:10.1039/b110414d
(2002)Doi:10.1021/jo010974p
(2002)Doi:10.1039/c4md00406j
(2015)Doi:10.1055/s-2002-20476
(2002)Doi:10.1007/BF00763240
()Doi:10.1039/b106021j
(2002)