Preparation and cytotoxic activity of some new rhodomycin derivatives bearing modifications in the sugar moiety

DOI: 10.7164/antibiotics.55.181

Source and publish data:

Journal of Antibiotics p. 181 - 190 (2002)

Update date:2022-08-02

Topics:

Authors:

Aligiannis, Nectarios

Pouli, Nicole

Marakos, Panagiotis

Skaltsounis, Alexios-Leandros

Florent, Jean-Claude

Perchellet, Elisabeth M.

Sperfslage, Bonnie J.

McIlvain, Corbin J.

Perchellet, Jean-Pierre

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Article abstract of DOI:10.7164/antibiotics.55.181

The synthesis and structural determination of a number of new rhodomycin derivatives, modified in the sugar part are described. The cytotoxicity against leukemic L1210 cells of these compounds is reported, along with β-rhodomycinone and two regioisomers of the above compounds, which were isolated during the synthetic procedure.

Full text of DOI:10.7164/antibiotics.55.181

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