Tetrahedron Letters p. 9351 - 9354 (1994)
Update date:2022-07-30
Topics:
Davis, Franklin A.
Reddy, Rajarathnam E.
Portonovo, Padma S.
Diethylaluminum cyanide adds stereoselectively to enantiopure sulfinimines 1 and 2 to give diastereomerically enriched α-amino nitriles 3 and 4 which are hydrolyzed in one step to α-amino acids 5 in >95percent ee and good yields.
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