Journal of Medicinal Chemistry p. 420 - 426 (1982)
Update date:2022-08-05
Topics:
Novinson
Springer
O'Brien
Scholten
Miller
Robins
A series of new 2-(alkylthio)-5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines have been prepared as inhibitors of cAMP phosphodiesterase from various tissues. These derivatives were prepared via ring closure of various requisite 3-amino-1,2,4-triazole
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