Bioorganic and Medicinal Chemistry p. 2045 - 2055 (2013)
Update date:2022-08-02
Topics:
Kusakabe, Ken-Ichi
Tada, Yukio
Iso, Yasuyoshi
Sakagami, Masahiro
Morioka, Yasuhide
Chomei, Nobuo
Shinonome, Satomi
Kawamoto, Keiko
Takenaka, Hideyuki
Yasui, Kiyoshi
Hamana, Hiroshi
Hanasaki, Kohji
Selective CB2 agonists have the potential for treating pain without central CB1-mediated adverse effects. Screening efforts identified 1,2-dihydro-3- isoquinolone 1; however, this compound has the drawbacks of being difficult to synthesize with two asymme
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