Total synthesis of the antitumor agent (-)-laulimalide

DOI: 10.1016/S0040-4039(02)00472-0

Source and publish data:

Tetrahedron Letters p. 3381 - 3383 (2002)

Update date:2022-09-26

Topics:

Authors:

Mulzer, Johann

Hanbauer, Martin

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(02)00472-0

A stereocontrolled synthesis of the title compound is described. Key steps are an allylsilane addition to a chiral acetal as the major coupling step and a Yamaguchi macrolactonization for ring closure.

Full text of DOI:10.1016/S0040-4039(02)00472-0

Products guided by the article

Product name:toluene-4-sulfonic acid 3-{6-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3,6-dihydro-2H-pyran-2-yl}-2-methyl-propyl ester

Cas No:527743-03-9

R&D Labs maybe for 527743-03-9

Fujian Wanke Pharmaceutical Co., LTD.

Contact:+86-598-5026002

Address:Economic development zone,jiangle county
NINGBO PANGS CHEM INT’L CO.,LTD.

Contact:+86-574-27666845

Address:FLOOR 21,BUILDING NO.11,XIN TIAN DI,NO.689 SHI JI ROAD,NINGBO CHINA
Synchemie Co., Ltd.

website:http://www.synchemie.com/

Contact:+86-574-87642758

Address:Room 901, Yinyi Bund Building， 132 Renmin Road
Jiangsu Seed Chem Co.,Ltd.

Contact:86-513-84128750/13773795976

Address:No.48.Youyi West Road ,Rudong Development Zone,Jiangsu Province,China
Anhui Eapearl Chemical Co., Ltd.

Contact:86-562-5858458

Address:358 South Huaihe Road

Relevant to this article

Doi:10.1007/BF03174770
(1939)
Doi:10.1021/ja01584a040
(1956)
Doi:10.1021/jm00257a014
(1974)
Cytotoxicity of some synthetic bis(arylidene) derivatives of cyclic ketones towards cisplatin-resistant human ovarian carcinoma cells

Doi:10.1007/s00044-020-02532-5
(2020)
Reaction of derivatives of methyl 2,3-O-benzylidene-6-deoxy-alpha-L-mannopyranoside with butyllithium: synthesis of methyl 2,6-dideoxy-4-O-methyl-alpha-L-erythro-hexopyranosid-3-ulose.

Doi:10.1016/S0008-6215(00)83147-X
(1976)
Doi:10.1246/bcsj.49.2614
(1976)

Article Doi