Research on L-Nucleosides. Synthesis and biological evaluation of a series of L- and D-2′,3′-Dideoxy-3′-[tris(methylthio)methyl]-β- pentofuranosyl nucleosides

Article abstract of DOI:10.1016/S0968-0896(02)00460-1

Novel nucleoside analogues of both D and L enantiomeric series were prepared by coupling reaction between a 2′,3′-dideoxy-3′-modified furanose moiety and four different nucleobases. Though in all cases anomeric mixtures of nucleosides were obtained, the p