A 'one-pot' phase transfer alkylation/hydrolysis of o-nitrotrifluoroacetanilides. A convenient route to N-alkyl o-phenylenediamines

Article abstract of DOI:10.1080/00397919608003827

A variety of o-nitrotrifluoroacetanilides undergo a one-pot alkylation/hydrolysis to give N-alkyl o-nitroanilines in 40-94% yield. Dimethylsulfate, benzyl bromide and 1-bromo-propane were used as the electrophiles.

Full text of DOI:10.1080/00397919608003827

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A “One-Pot” Phase Transfer
Alkylation/Hydrolysis of o-
Nitrotrifluoroacetanilides. A
Convenient Route to N-ALKYL
o-Phenylenediamines
Samuel A. Brown a & Carmelo J. Rizzo a
a Department of Chemistry , Vanderbilt University ,
Box 1822, Station B;, Nashville, TN, 37235
Published online: 23 Aug 2006.
To cite this article: Samuel A. Brown & Carmelo J. Rizzo (1996) A “One-Pot” Phase
Transfer Alkylation/Hydrolysis of o-Nitrotrifluoroacetanilides. A Convenient Route to
N-ALKYL o-Phenylenediamines, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 26:21, 4065-4080, DOI:
10.1080/00397919608003827
To link to this article: http://dx.doi.org/10.1080/00397919608003827
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