Organic and Biomolecular Chemistry p. 2897 - 2901 (2017)
Update date:2022-08-03
Topics:
Zhang, Yaxing
Dong, Jianyu
Liu, Lixin
Liu, Long
Zhou, Yongbo
Yin, Shuang-Feng
Mn-Catalyzed oxidative amination of benzylic C(sp3)-H bonds with nitriles is disclosed, which enables the synthesis of a broad range of secondary amides in moderate to excellent yields under mild conditions. The interaction between Mn(iii) and DDQ facilitates the oxidation and makes it highly efficient and selective.
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