
Bioorganic and Medicinal Chemistry Letters p. 51 - 56 (1998)
Update date:2022-08-03
Topics:
Owens
Harrison
Moseley
Swain
Sadowski
Cascieri
Heterocyclic replacements for the carboxamido group of the previously disclosed phenylglycinol-based human NK1 (hNK1) receptor antagonists have been investigated, ultimately leading to acyclic compounds with sub-nanomolar affinity for the hNK1 receptor.
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