Organic Letters p. 5529 - 5531 (2008)
Update date:2022-08-05
Topics:
Hu, Mingyu
Li, Junqi
Yao, Shao Q.
(Chemical Equation Presented) A panel of small molecule-based MMP inhibitors containing rhodanine warheads was assembled using "one-pot" click chemistry. Upon biological screening, moderate inhibitors were identified which specifically targets MMP-7 and MMP-13 over other MMPs.
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