Organic and Biomolecular Chemistry p. 3133 - 3135 (2011)
Update date:2022-09-26
Topics:
Lv, Pei
Huang, Kanglun
Xie, Longguan
Xu, Xiaohua
A concise and efficient synthesis of benzo[c]phenanthridines was accomplished by the palladium-catalyzed ring-opening coupling of azabicyclic alkene with o-iodobenzoates, followed by tandem cyclization. The strategy was successfully applied in the total synthesis of benzo[c]phenanthridine alkaloids such as sanguinarine, chelerythrine, nitidine and avicine.
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(1931)
