Rigidified multivalent lactose molecules and their interactions with mammalian galectins: A route to selective inhibitors

DOI: 10.1039/b210923a

Source and publish data:

Organic and Biomolecular Chemistry p. 803 - 810 (2003)

Update date:2022-08-03

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Authors:

Vrasidas, Ioannis

Andre, Sabine

Valentini, Paola

Boeck, Corina

Lensch, Martin

Kaltner, Herbert

Liskamp, Rob M.J.

Gabius, Hans-J.

Pieters, Roland J.

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Article abstract of DOI:10.1039/b210923a

New and rigid multivalent lactose molecules were prepared. The structures contain lactose-2-aminothiazoline units at the periphery that were formed from a cyclisation of the thiourea sulphur onto the triple bond of the spacer. The lactosides were evaluate

Full text of DOI:10.1039/b210923a

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