Efficient reduction of azides to amines with tributylstannane. High-yield syntheses of amino and diamino deoxynucleosides

Article abstract of DOI:10.1016/0040-4039(91)80150-5

Treatment of unprotected azido-deoxynucleosides with tributylstannane/AIBN in hot benzene/DMAC (or silyl-protected derivatives in benzene) resulted in formation of the corresponding amino-deoxynucleosides in high isolated yields. A radical process is indicated.