Bioorganic and Medicinal Chemistry Letters p. 771 - 774 (1998)
Update date:2022-07-30
Topics:
Bright, Colin
Brown, Thomas J.
Cox, Paul
Halley, Frank
Lockey, Peter
McLay, Iain M.
Moore, Una
Porter, Barry
Williams, Robert J.
A series of phenothiazines demonstrating inhibition of RANTES binding to THP-1 cell membranes has been identified. The lead compound RP23618 (IC50 = 3 μM) was found to inhibit specific binding of 125I-RANTES, but not 125I-MCP-1 to THP-1 cell membranes and furthermore to antagonise RANTES, but not MCP-1-induced chemotaxis of THP-1 cells.
View MoreContact:+36(21)2523420
Address:Head office: 1102 Budapest, SZENT LASZLO TER 24/B. 1/1., HUNGARY / CHINA
Contact:0571-
Address:zhejing
Shanghai Pinewood Fine Chemical Co., Ltd.
website:http://www.pinewoodchem.com
Contact:0086-21-62417129，62414096
Address:Suite B, 27F, No.2, Lane 600, Tianshan Road, Shanghai
Xian Changyue Biological Technology Co., Ltd.
website:https://www.xachangyue.com/
Contact:+86-029-88211911
Address:Keji Road NO.70
Qingdao Wanyuan Mountain Biotech Co.Ltd
website:http://www.bionutrichem.com.cn
Contact:+86-0532-66720179
Address:qingdao
Doi:10.1002/zaac.200390149
(2003)Doi:10.1021/ja0358044
(2003)Doi:10.1021/ja01153a504
(1951)Doi:10.1007/BF02234855
(1999)Doi:10.1002/anie.201504072
(2015)Doi:10.1016/S0020-1693(00)91707-9
(1976)
