A short, convenient synthesis of 2-arylglycidates via aryl-grignard addition to an α-bromopyruvate

Article abstract of DOI:10.1080/00397919908086003

A simple procedure has been developed for the preparation of a series of 2-arylglycidates required for herbicidal evaluation. Treatment of the α- bromopyruvate 5 with various aryl Grignard reagents at low temperature gave directly the glycidates 4. Saponification of these then afforded the desired sodium salts 7.

Full text of DOI:10.1080/00397919908086003

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A Short, Convenient Synthesis of
2-Arylglycidates via Aryl-Grignard
Addition to an α-Bromopyruvate
Michael E. Jung a , Werner Mengel b & Trevor W. Newton b
a Department of Chemistry and Biochemistry , University of
California , Los Angeles, CA, 90095, USA
b Cyanamid Forschung GmbH , Postfach 100, D-55270,
Schwabenheim, Germany
Published online: 17 Sep 2007.
To cite this article: Michael E. Jung , Werner Mengel & Trevor W. Newton (1999) A Short,
Convenient Synthesis of 2-Arylglycidates via Aryl-Grignard Addition to an α-Bromopyruvate,
Synthetic Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 29:21, 3659-3666, DOI: 10.1080/00397919908086003
To link to this article: http://dx.doi.org/10.1080/00397919908086003
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