Tetrahedron Letters p. 5051 - 5054 (1980)
Update date:2022-07-29
Topics:
Knght, David W.
Nott, Andrew P.
Dianions (3) and (6) can be generated in high yield from the corresponding thiophencarboxylic acids with lithium diisopropylamide and react with a number of representative electrophiles to give fair to good yields of 5-substituted-thiophen-2-carboxylic acids and 2-substituted thiophen-3-carboxylic acids respectively.
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Doi:10.1016/j.ejmech.2019.02.023
(2019)Doi:10.1002/ejoc.200300081
(2003)Doi:10.1021/jo00879a038
(1976)Doi:10.1002/hlca.19480310634
(1948)Doi:10.1016/0009-2614(93)85080-8
(1993)Doi:10.1021/ja01278a039
(1938)
