Tetrahedron Letters p. 273 - 276 (1984)
Update date:2022-08-05
Topics: NMR spectroscopy High-performance liquid chromatography (HPLC) Reaction Conditions Lactonization
Gais, H.-J.
A highly efficient method for the macrolactonization of seco-acids is described.Seco-acids are converted into stable enolesters 3 by the acetylene 1, which are cyclized under proton or Lewis acid catalysis.This new method has been successfully applied to the lactonization of the 7-epi-brefeldin A seco-acids 8a, b.
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Doi:10.1021/ja034563x
(2003)Doi:10.1055/s-1978-24752
(1978)Doi:10.1021/acs.jmedchem.5b00775
(2015)Doi:10.1080/10426500008042099
(2000)Doi:10.1016/S0040-4039(03)01526-0
(2003)Doi:10.1002/ejic.201200322
(2012)
