
Tetrahedron Letters p. 2405 - 2408 (1991)
Update date:2022-08-05
Topics:
Otera, Junzo
Wakahara, Yoshiyuki
Kamei, Hidenobu
Sato, Tsuneo
Nozaki, Hitosi
Fukuzumi, Shunichi
10-Methylacridinium perchlorate (1) effectively promotes various reactions of ketene silyl acetals: aldol and Michael addition products are obtained with aldehydes, ketones, acetals, and α-enones.The reactions exhibit unusual dependency upon 1, namely the yields are excellent when a catalytic amount of 1 is employed whereas no desired products are accessible by the use of 1 in a stoichiometric quantity.A novel catalytic cycle is proposed.
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Doi:10.1039/DT9760000953
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