Tetrahedron Letters (2021)
Update date:2022-07-29
Topics:
Leister, Jeffrey
Chao, Darrian
Billingsley, Kelvin L.
Prenyl or dimethylallyl groups are common structural motifs in natural products and small molecule therapeutics. In this report, we describe a palladium-catalyzed method for the cross-coupling of aryl and heteroaryl boronic acids with prenyl alcohol. Catalyst systems based on dialkylbiaryl phosphines were highly active for this transformation. These supporting ligands provided opportunities for tuning the efficiency and regioselectivity of carbon–carbon bond formation. In addition, this method was further extended to the cross-coupling of symmetrical allylic alcohols with aryl boronic acids.
Weifang Ocean Trading Co., Ltd.
Contact:+86-536-2081155
Address:Room2606, Yuqing Building, 518#, Yuquan Road, High-tech Development Zone, Weifang City, Shandong Province, China
website:http://www.tcfinechem.com/
Contact:18681346930
Address:baifu town,whou district
Hangzhou Taiyan Trading Co., Ltd(expird)
Contact:+86-13777583958
Address:NO.63, Xingyi Street, Xihu District, Hangzhou, Zhejiang, China
Sichuan Sangao Biochemical Co., Ltd
Contact:+86-28-84874233
Address:19F, Bldg.2, Shudu Center, Tianfu 2nd St., Hi-tech zone, Chengdu 610041, Sichuan Province, China.
Jiande City Silibase Silicone New Material Manufacture Co., Ltd.
Contact:15967177856
Address:Genglou Industrial Development Area
Doi:10.1246/bcsj.67.2532
(1994)Doi:10.1021/ja01100a051
(1953)Doi:10.1021/ja00064a020
(1993)Doi:10.1016/0022-1902(70)80498-5
(1970)Doi:10.1139/v93-030
(1993)Doi:10.1016/j.tetasy.2006.09.004
(2006)
