An allylation-metathesis sequence as a convergent strategy towards enantiopure equivalents of highly functionalized cyclic dienes

Article abstract of DOI:10.1016/S0040-4039(03)01791-X

Highly enantioenriched equivalents of cyclic dienes have been readily prepared by asymmetric allylation of unsaturated aldehydes using a chiral allyltitanium reagent, followed by a ring-closing metathesis. The resulting β-hydroxy allylsilanes react stereo