Bioorganic and Medicinal Chemistry Letters p. 4048 - 4052 (2005)
Update date:2022-08-05
Topics:
Romagnoli, Romeo
Baraldi, Pier Giovanni
Jung, M. Katherine
Iaconinoto, Maria Antonietta
Carrion, Maria Dora
Remusat, Vincent
Preti, Delia
Tabrizi, Mojgan Aghazadeh
Francesca, Fruttarolo
De Clercq, Erik
Balzarini, Jan
Hamel, Ernest
A new series of compounds, in which the 2-amino-4-methoxyphenyl ring of phenstatin analogue 5 was replaced with 2- or 3-amino-benzoheterocycles, was synthesized and evaluated for antiproliferative activity and inhibition of colchicine binding. The lack of
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