
Journal of Medicinal Chemistry p. 398 - 400 (1977)
Update date:2022-08-05
Topics:
Angeli
Melchiorre
Giannella
Pigini
Cingolani
The synthesis of some cyclohexane analogues of deoxamuscarine is reported. Stereochemical aspects are discussed on the basis of IR and NMR spectra. Muscarinic activity, measured on guinea pig ileum, shows a sharp drop when comparison is made with the cyclopentyl analogues.
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(2015)