Tetrahedron p. 6455 - 6464 (2003)
Update date:2022-07-29
Topics:
Arnó, Manuel
Betancur-Galvis, Liliana
Bueno-Sanchez, Juan G.
González, Miguel A.
Zaragozá, Ramón J.
The synthesis and antiviral properties of several scopadulcic acid analogues functionalized at C-6/C-7 and C-13 is reported. The preparation of advanced intermediates for the synthesis of scopadulcic acid B/scopadulciol analogues is also described. The biological study revealed the importance of polar groups at C-13, while the stereochemistry at C-8 was not critical for activity.
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