New reagent for the optical resolution of ketones: (-) (1R, 2R, 5R)-5-methyl-2-(1-mercapto-1-methylethyl)-cyclohexanol. Application to trans dimethyl cyclopentanone-3,4-dicarboxylate

Article abstract of DOI:10.1016/S0957-4166(00)80357-2

(-) (1R, 2R, 5R)-5-methyl-2-(1-mercapto-1-methylethyl)-cyclohexanol was shown to be a very powerful agent for the optical resolution of ketones. It was used for the resolution of trans dimethyl cyclopentanone-3,4-dicarboxylate combined with the epimerizat