Journal of Medicinal Chemistry p. 71 - 75 (1982)
Update date:2022-08-04
Topics: Synthesis Analogues Biological Activity Aromatic Fluorinated Retinoic Acids 6-Fluoro Analogues
Lovey, Allen J.
Pawson, Beverly A.
Several analogues (15a-e) of methyl (E,E,Z,E)-3,7-dimethyl-6-fluoro-9-(4-methoxy-2,3,6-trimethylphenyl)nonatetraenoate (15f), which had been found to cause a marked regression of chemically induced skin papillomas in mice, were prepared.Two synthetically
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